Illustrative examples of knee and hip implants made by using additive manufacturing technique
When a part of the body stops working, either because of disease or trauma, implants made of biomaterials can be used as replacements. The material choice is not trivial, and depending on what the material is meant to replace, e.g. a piece of bone or a knee joint, there are different requirements on its chemical and mechanical properties. The material needs to be biocompatible, i.e. have the ability to perform with an appropriate host response in a specific situation. This can appear to be a vague definition, but it is a reflection of the importance of putting the material into context in order to evaluate its function. That is, biomaterials need to be evaluated in terms of their function in their system as far as possible, and we put great weight on this in our research.
The BioMaterial Systems Group focuses on the study, development and characterization of new materials and implant designs, mainly for orthopaedic applications, in their systems. Focus lies on injectable materials as well as materials and implant design development through additive manufacturing (3D-printing). We also develop and characterize wear-resistant materials for joint applications. Experimental and computational (e.g. FE) models are used to study the materials and implant/tissue interactions, also inside micro-CTs. Early biocompatibility studies may be done within the group, while when moving further towards the clinical application and/or commercial product, collaborations with e.g. Uppsala University Hospital are employed, in particular with the OrthoLab and the Biomaterials for Trauma Groups.
The BMS group performs an indisciplinary research and work within the following competence fields:
- Materials development
BMS GROUP RESEARCH PROJECTS:
Du, Xiaoyu; Zhou, Yijun; Li, Lingzhe; Persson, Cecilia; Ferguson, Stephen J.
The porous cantilever beam as a model for spinal implants: Experimental, analytical and finite element analysis of dynamic properties
Geissel, Felix J.; Platania, Varvara; De Berardinis, Niccoló; Skjöldebrand, Charlotte; Belibasakis, Georgios N.; Persson, Cecilia; Hulsart-Billström, Gry; Chatzinikolaidou, Maria; Sotiriou, Georgios A.
Nanostructured Ag-Bioglass Implant Coatings with Antibacterial and Osteogenic Activity
Echeverri Correa, Estefania; Skjöldebrand, Charlotte; O'Callaghan, Paul; Palmquist, Anders; Kreuger, Johan; Hulsart Billström, Gry; Persson, Cecilia
Fe and C additions decrease the dissolution rate of silicon nitride coatings and are compatible with microglial viability in 3D collagen hydrogels
Prof. Cecilia Persson is now Guest Editor for Materials' Special Issue on Additive Manufacturing of Biomaterials. In this Special Issue, the focus is on the development, design, and characterization of additively manufactured biomaterials. This includes new polymers, ceramics, metals, as well as composites, specifically developed for use as biomaterials.
Please, consider submitting your paper here:https://www.mdpi.com/journal/materials/special_issues/biomaterial_AM_3D-printing
Deadline for manuscript submissions: 31 May 2021.